The following are the most common screen reader/browser combinations used among vision impaired users.
JAWS (Windows based software. Need to purchase license) + Internet Explorer, Chrome or FF
NVDA (this is a free, open source, Windows based software) + Firefox - 72%
JAWS (Windows based) + Internet Explorer, Chrome or FF - 61%
VoiceOver (iOS) + Safari - 47%
JAWS is not compatible with Microsoft Edge.
...
https://www.nvaccess.org/download/
JAWS Screen Reader
JAWS screen reader by Freedom Scientific
Screen reader/Browser Stats
https://webaim.org/projects/screenreadersurvey8screenreadersurvey9/#browsercombos